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In both the hypophysis and hypothalamus there are cortisol receptors through which cortisol can exert a feedback inhibition of ACTH or CRH release. By means of these cortisol “sensors,” the regulatory centers can monitor whether the actual blood level of the hormone corresponds to the “set-point. ”
Hypertension infrequently results from another disease, such as a catecholamine- secreting tumor (pheochromocytoma); in most cases the cause cannot be determined: essential (primary) hypertension. Antihypertensive drugs are indicated when blood pressure cannot be sufficiently controlled by means of weight reduction or a lowsalt diet. |
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